Endocrine Abstracts

Introduction: During adrenal insufficiency (AI), glucocorticoid treatment is supposed to be neutral on the metabolic parameters of patients. However, recent data from the literature report that this corticosteroid replacement therapy increases the metabolic risk. The aim of our work was to determine the metabolic and cardiovascular impact of hydrocortisone (HC) replacement therapy during peripheral AI.Patients and methods: This was a descriptive and anal...

Introduction: Hydrocortisone (HC) is the most widely used replacement molecule in the treatment of adrenal insufficiency (AI). This substitution treatment is far from ideal especially as it is impossible to reproduce the nycthemeral cycle of cortisol with its current galenic form which has a short half-life. The aim of our work was to determine the impact of HC treatment of peripheral AI on the long-term quality of life and sleep.Patients and methods: Th...

Introduction: The treatment of adrenal insufficiency (AI) is based on long-term glucocorticoid substitution. Hydrocortisone (HC) is the most commonly used substitution molecule. The aim of our work was to determine the long-term bone impact of patients with peripheral AI.Patients and methods: This is a descriptive and analytical study involving 77 patients with peripheral IS (66 women and 11 men), all treated with HC. For each patient, we determined the ...

Introduction: Diabetes distress (DD) refers to the emotional burdens and worries, often hidden, that are part of the spectrum of the patient experience when managing a chronic and demanding disease like diabetes. The objective of this work was to determine the prevalence of DD and its clinical determinants in type 2 diabetic patients.Patients and methods: Cross-sectional study conducted on 92 type 2 diabetic patients who consulted on an outpatient basis ...

Introduction: Medication Adherence (MA) is the extent to which patients follow medical instructions. Poor MA is frequently encountered in the majority of chronic diseases, including diabetes. The aim of our study was to evaluate MA in patients with poorly controlled type 2 diabetes mellitus (T2DM).Patients and methods: We conducted a cross-sectional study over a period of 2 months, including patients with poorly controlled T2DM, followed at the endocrino...

Introduction: Acromegaly is a rare hormonal condition that results from an excess amount of growth hormone (GH) in the body. A variety of complications have been reported in patients with acromegaly including cardiovascular diseases, diabetes mellitus or respiratory disorders. In addition, Acromegaly is associated with gastrointestinal complications. The aim of this study was to evaluate gastrointestinal complications and their impact on the quality of life among patients suff...

Introduction: Dietary practices are essential in diabetes control and acquiring HbA1c target. The aim of our work is to evaluate the prevalence of dietary education practice in a type 2 diabetes population and its associated factors.Methods: Cross-sectional study enrolling 84 type 2 diabetes patients followed up in the outpatient endocrinology department. The data was collected through a questionnaire in face-to-face interviews with patients. Age, body m...

Introduction: Thyroid diseases have been known to cause haemostatic changes, either tendency to bleeding or thrombosis. We report a case of a patient with primary hypothyroidism presenting with spontaneous bleeding and jugular thrombosis.Case report: An 85-year old patient with no medical history was admitted to the endocrinology department with primary auto-immune hypothyroidism. Hypothyroidism was suspected because of severe loss of weight and appetite...

Introduction: Thyroid hormones in fluence kidney function and thereby might alter serum urate levels, a major risk factor for gouty arthritis. Previous research documented a high prevalence of elevated levels of Uric acid in primary hypothyroid patients. We present the case of an incident gout attack in a patient with primary hypothyroidism.Case report: A 72-year-old male was hospitalized for a primary hypothyroidism complicated by a rhabdomyolysis. Labo...

Introduction: Allowing to have a good glycemic control, presenting no contraindications and contributing to the optimization of the general and nutritional state, insulin remains a treatment of choice for the diabetic elderly. Proper injection technique is key to achieving and maintaining goal-level diabetes control. The objective of our study was to assess insulin injection techniques in elderly subjects with type 2 diabetes.Methods: A cross-sectional s...